Publications Archive for 2007


Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells

By Grudzien-Nogalska E., Jemielity J., Kowalska J., Darzynkiewicz E., Rhoads R.E.,

Published in RNA 13 (2007) 1745 - 1755

A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain

By Kowalska J., Lewdorowicz M., Darzynkiewicz E., Jemielity J.,

Published in Tetrahedron Lett. 48 (2007) 5475 - 5479

A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain


Synthesis of anti-reverse cap analogs (ARCAs) and their applications in mRNA translation and stability

By Grudzien-Nogalska E., Stepinski J., Jemielity J., Zuberek J., Stolarski R., Rhoads R.E., Darzynkiewicz E.,

Published in Method Enzymol. 431 (2007) 203 - 227

Interaction of human decapping scavenger with 5 ‘ mRNA cap analogues: structural requirements for catalytic activity

By Darzynkiewicz Z.M., Bojarska E., Kowalska J., Lewdorowicz M., Jemielity J., Kalek M., Stepinski J., Davis R.E., Darzynkiewicz E.,

Published in J Phys-Condens Mat. 19 (2007) art. no. 285217

Weak binding affinity of human 4EHP for mRNA cap analogs

By Zuberek J., Kubacka D., Jablonowska A., Jemielity J., Stepinski J., Sonenberg N., Darzynkiewicz E.,

Published in RNA 13 (2007) 691 - 697

Assignment of the absolute configuration of P-chiral 5’mRNA cap analogues containing phosphorothioate moiety

By Kowalska J., Lewdorowicz M., Zuberek J., Bojarska E., Stepinski J., Stolarski R., Darzynkiewicz E., Jemielity J.,

Published in Nucleos. Nucleot. Nucl. Acids 26 (2007) 1301 - 1305

Synthesis of H-3 and C-13 labeled mRNA cap dinucleotides-useful tools for NMR, biochemical, and biological studies

By Jemielity J., Stolarski R., Darzynkiewicz E.,

Published in Nucleos. Nucleot. Nucl. Acids 26 (2007) 1315 - 1319

Solid-supported synthesis of 5 ‘-mRNA cap-4 from trypanosomatids

By Lewdorowicz M., Jemielity J., Kierzek R., Shapira M., Stepinski J., Darzynkiewicz E.,

Published in Nucleos. Nucleot. Nucl. Acids 26 (2007) 1329 - 1333

Kinetics of C elegans DcpS cap hydrolysis studied by fluorescence spectroscopy

By Wierzchowski J., Pietrzak M., Stepinski J., Jemielity J., Kalek M., Bojarska E., Jankowska-Anyszka M., Davis R.E., Darzynkiewicz E.,

Published in Nucleos. Nucleot. Nucl. Acids 26 (2007) 1339 - 1348

Affinity of dinucleotide cap analogues for human decapping scavenger (hdcps)

By Darzynkiewicz Z.M., Bojarska E., Stepinski J., Jemielity J., Jankowska-Anyszka M., Davis R.E., Darzynkiewicz E.,

Published in Nucleos. Nucleot. Nucl. Acids 26 (2007) 1349 - 1352