Publications Archive for 2010


Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

By Kuhn A.N., Diken M., Kreiter S., Selmi A., Kowalska, J., Jemielity, J., Darzynkiewicz, E., Huber, C., Tureci O., Sahin, U.,

Published in Gene Therapy 17 (2010) 961 - 971

Synthetic mRNA cap analogs with modified triphosphate bridge – synthesis, applications and prospects

By Jemielity, J., Kowalska, J., Rydzik, A. M., Darzynkiewicz, E.,

Published in New J. Chem. 34 (2010) 829 - 844

Synthetic mRNA cap analogs with modified triphosphate bridge – synthesis, applications and prospects


Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications

By Strenkowska M., Kowalska J., Lukaszewicz M., Zuberek J., Su W., Rhoads R. E., Darzynkiewicz E., Jemielity J.,

Published in New J. Chem. 34 (2010) 993 - 1007

Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications


Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies

By Wypijewska A., Bojarska E., Stepinski, J., Jankowska-Anyszka, M., Jemielity J., Davis, R.E., Darzynkiewicz E.,

Published in FEBS J. 299 (2010) 3003 - 3013

Dual activity of certain HIT-proteins: A. thaliana Hint4 and C-elegans DcpS act on adenosine 5 ‘-phosphosulfate as hydrolases (forming AMP) and as phosphorylases (forming ADP)

By Guranowski A., Wojdyla A.M., Zimny J., Wypijewska A., Kowalska J., Jemielity J., Davis, R.E., Bieganowski P.,

Published in FEBS Lett. 584 (2010) 93 - 98

Recognition of different nucleotidyl-derivatives as substrates of reactions catalyzed by various HIT-proteins

By Guranowski A., Wojdyla A.M., Zimny J., Wypijewska A., Kowalska J., Lukaszewicz M., Jemielity J., Darzynkiewicz E., Jagiello A., Bieganowski P.,

Published in New J. Chem. 34 (2010) 888 - 893