Publications Archive for 2013


Synthesis and evaluation of stability of m3G-CAP analogues in serum-supplemented medium and cytosolic extract

By Malgorzata Honcharenko, Malgorzata Zytek, Burcu Bestas, Pedro Moreno, Jacek Jemielity, Edward Darzynkiewicz, C.I. Edvard Smith, Roger Strömberg,

Published in Bioorganic & Medicinal Chemistry 21 (2013) 7921–7928

Synthesis and evaluation of stability of m3G-CAP analogues in serum-supplemented medium and cytosolic extract


Analysis of Decapping Scavenger (DcpS)-cap complex using modified cap analogs reveals molecular determinants for efficient cap binding

By Anna Wypijewska del Nogal, Marius D. Surleac, Joanna Kowalska, Maciej Lukaszewicz, Jacek Jemielity, Martin Bisaillon, Edward Darzynkiewicz, Adina L. Milac, Elzbieta Bojarska,

Published in FEBS Journal 280 (2013) 6508–6527

Analysis of Decapping Scavenger (DcpS)-cap complex using modified cap analogs reveals molecular determinants for efficient cap binding


Synthesis and evaluation of fluorescent cap analogues for mRNA labelling

By Marcin Ziemniak, Mariusz Szabelski, Maciej Lukaszewicz, Anna Nowicka, Edward Darzynkiewicz, Zbigniew Wieczorek, Robert E. Rhoads, Jacek Jemielity,

Published in RSC Advances 3 (2013) 20943-20958

Synthesis and evaluation of fluorescent cap analogues for mRNA labelling


Hint2, the mitochondrial nucleoside 5′-phosphoramidate hydrolase; properties of the homogeneous protein from sheep (Ovis aries) liver

By Ewa Bretes, Anna M. Wojdyła-Mamoń, Joanna Kowalska, Jacek Jemielity, Renata Kaczmarek, Janina Baraniak, Andrzej Guranowski,

Published in Acta Biochimica Polonica 60 (2013) 249-254

The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation

By Marcin Warminski, Joanna Kowalska, Janina Buck, Joanna Zuberek, Maciej Lukaszewicz, Corina Nicola, Andreas N. Kuhn , Ugur Sahin, Edward Darzynkiewicz, Jacek Jemielity,

Published in Bioorganic & Medicinal Chemistry Letters 23 (2013) 3753–3758

The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation


Magnetic-nanoparticle-decorated polypyrrole microvessels: Toward encapsulation of mRNA cap analogs

By Krystyna Kijewska, Anita Jarzębińska, Joanna Kowalska, Jacek Jemielity, Daria Kępińska, Jacek Szczytko, Marcin Pisarek, Katarzyna Wiktorska, Jarosław Stolarski, Pawel G. Krysinski, Andrzej Twardowski, Maciej Mazur,

Published in Biomacromolecules 14 (2013) 1867−1876

Magnetic-nanoparticle-decorated polypyrrole microvessels: Toward encapsulation of mRNA cap analogs


Potential therapeutic applications of RNA cap analogs

By Marcin Ziemniak, Malwina Strenkowska, Joanna Kowalska, Jacek Jemielity,

Published in Future Medicinal Chemistry 5 (2013) 1141-1172

Efficient and rapid synthesis of nucleoside diphosphate sugars from nucleoside phosphorimidazolides

By Pawel Dabrowski-Tumanski, Joanna Kowalska and Jacek Jemielity,

Published in Eur J Org Chem 2013 (2013) 2147 - 2154

Efficient and rapid synthesis of nucleoside diphosphate sugars from nucleoside phosphorimidazolides


Synthetic mRNAs with Superior Translation and Stability Properties

By Ewa Grudzien-Nogalska, Joanna Kowalska, Wei Su, Andreas N. Kuhn, Sergey V. Slepenkov, Edward Darzynkiewicz, Ugur Sahin, Jacek Jemielity, Robert E. Rhoads ,

Published in Methods in Molecular Biology 969 (2013) 55-72

mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end

By Wei Su, Sergey V. Slepenkov, Michael K. Slevin, Shawn M. Lyons, Marcin Ziemniak, Joanna Kowalska, Edward Darzynkiewicz, Jacek Jemielity, William F. Marzluff and Robert E. Rhoads,

Published in RNA 19 (2013) 1-16

mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end