Publications Archive for 2021


Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy

By Anna Wojtczak, Renata Kasprzyk, Marcin Warmiński, Krystian Ubych, Dorota Kubacka, Paweł J. Sikorski, Jacek Jemielity, Joanna Kowalska,

Published in Scientific Reports 11 (2021) 7687

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation

By Ryan W. Tibble, Anais Depaix, Joanna Kowalska, Jacek Jemielity, John D. Gross,

Published in Nature Chemical Biology 17 (2021) 615–623

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation


Tricks and threats of RNA viruses – towards understanding the fate of viral RNA

By Łukasz Markiewicz, Karolina Drążkowska, Paweł J. Sikorski,

Published in RNA Biology 18 (2021) 669–687

Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as 19F NMR Probes

By Mikołaj Chromiński, Marek R. Baranowski, Sebastian Chmieliński, Joanna Kowalska, Jacek Jemielity,

Published in Journal of Organic Chemistry 85 (2021) 3440–3453

Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as 19F NMR Probes


Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect

By Marcin Warmiński, Joanna Kowalska, Elżbieta Nowak, Dorota Kubacka, Ryan Tibble, Renata Kasprzyk, Paweł J. Sikorski, John D. Gross, Marcin Nowotny, Jacek Jemielity,

Published in ACS Chemical Biology 16 (2021) 334–343

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect