Publications Archive

Fluorescent turn-on probes for the development of binding and hydrolytic activity assays for mRNA cap-recognising proteins

By Renata Kasprzyk, Beata Jagoda Starek, Sylwia Ciechanowicz, Dorota Kubacka, Joanna Kowalska, Jacek Jemielity,

Published in Chemistry - A European Journal 25 (2019) 6728-6740

Fluorescent turn-on probes for the development of binding and hydrolytic activity assays for mRNA cap-recognising proteins

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Nicotinamide-Containing Di- and Trinucleotides as Chemical Tools for Studies of NAD-Capped RNAs

By Agnieszka Młynarska-Cieślak, Anais Depaix, Ewa Grudzień-Nogalska, Paweł J. Sikorski, Marcin Warmiński, Megerditch Kiledjian, Jacek Jemielity, Joanna Kowalska,

Published in Organic Letters 20 (2018) 7650–7655

Nicotinamide-Containing Di- and Trinucleotides as Chemical Tools for Studies of NAD-Capped RNAs

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mRNAs biotinylated within the 5′ cap and protected against decapping: new tools to capture RNA–protein complexes

By Sylwia Bednarek, Vanesa Madan, Paweł J. Sikorski, Ralf Bartenschlager, Joanna Kowalska, Jacek Jemielity,

Published in Philosophical Transactions of The Royal Society B 373 (2018)

mRNAs biotinylated within the 5′ cap and protected against decapping: new tools to capture RNA–protein complexes

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Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation

By Katharina Essig, Nina Kronbeck, Joao C. Guimaraes, Claudia Lohs, Andreas Schlundt, Anne Hoffmann, Gesine Behrens, Sven Brenner, Joanna Kowalska, Cristina Lopez-Rodriguez, Jacek Jemielity, Helmut Holtmann, Kristin Reiche, Jörg Hackermüller, Michael Sattler, Mihaela Zavolan , Vigo Heissmeyer,

Published in Nature Communications 9 (2018) 3810

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Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators

By Sylwia Walczak, Paweł Sikorski, Renata Kasprzyk, Joanna Kowalska, Jacek Jemielity,

Published in Organic and Biomolecular Chemistry 16 (2018) 6741-6748

Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators

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ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions

By Przemysław Wanat, Renata Kasprzyk, Michał Kopciał, Paweł J. Sikorski, Dominika Strzelecka, Jacek Jemielity, Joanna Kowalska,

Published in Chemical Communications 54 (2018) 9773-9776

ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions

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5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes

By Błażej A. Wojtczak, Paweł J. Sikorski, Kaja Fac-Dąbrowska, Anna Nowicka, Marcin Warmiński, Dorota Kubacka, Elżbieta Nowak, Marcin Nowotny, Joanna Kowalska, Jacek Jemielity,

Published in Journal of the American Chemical Society 140 (2018) 5987-5999

5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes

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Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis

By JS Mugridge, RW Tibble, M Ziemniak, J Jemielity, JD Gross,

Published in Nature communications 9 (2018) 1152

Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis

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7-Methylguanosine monophosphate analogues with 5′-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase

By Mateusz Kozarski, Dorota Kubacka, Błażej A. Wojtczak, Renata Kasprzyk, Marek Baranowski, Joanna Kowalska,

Published in Bioorganic & Medicinal Chemistry 26 (2018) 191-199

7-Methylguanosine monophosphate analogues with 5′-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase

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Azido-Functionalized 5ʹ-Cap Analogs for Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells

By Adam Mamot, Pawel J. Sikorski, Marcin Warminski, Joanna Kowalska, Jacek Jemielity,

Published in Angewandte Chemie International Edition 56 (2017) 10.1002/anie.201709052

Azido-Functionalized 5ʹ-Cap Analogs for Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells

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Fluorescent turn-on probes for the development of binding and hydrolytic activity assays for mRNA cap-recognising proteins

Nicotinamide-Containing Di- and Trinucleotides as Chemical Tools for Studies of NAD-Capped RNAs

mRNAs biotinylated within the 5′ cap and protected against decapping: new tools to capture RNA–protein complexes

Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation

Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators

ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions

5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes

Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis

7-Methylguanosine monophosphate analogues with 5′-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase

Azido-Functionalized 5ʹ-Cap Analogs for Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells

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