Publications Archive


eIF4E phosphorylation by MST1 reduces translation of a subset of mRNAs, but increases lncRNA translation

By Kyung-Won Min, Sylvia Davila, Richard W. Zealy, Lawson T. Lloyd, In Young Lee, Rumi Lee, Kyung Hye Roh, Ahjin Jung, Jacek Jemielity, Eui-Ju Choi, Je-Hyun Yoon,

Published in Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1860 (2017) 761–772

Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses

By Barbara Kroczynska, Gavin T. Blyth, Robert L. Rafidi, Beata Majchrzak-Kita, Lucy Xu, Diana Saleiro, Ewa M. Kosciuczuk, Jacek Jemielity, Bing Su, Jessica K. Altman, Elizabeth A. Eklund, Eleanor N. Fish, Leonidas C. Platanias,

Published in J. Biol. Chem. 292 (2017) 4743-4752

Applications of Phosphate Modification and Labeling to Study (m)RNA Caps

By Marcin Warminski, Pawel J. Sikorski, Joanna Kowalska, Jacek Jemielity,

Published in Topics in Current Chemistry 375 (2017) Art no. 16

Applications of Phosphate Modification and Labeling to Study (m)RNA Caps


A novel route for preparing 5′ cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistry

By Sylwia Walczak, Anna Nowicka, Dorota Kubacka, Kaja Fac, Przemyslaw Wanat, Seweryn Mroczek, Joanna Kowalska, Jacek Jemielity,

Published in Chemical Science 8 (2017) 260 - 267

A novel route for preparing 5′ cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistry


Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential

By Malwina Strenkowska, Renata Grzela, Maciej Majewski, Katarzyna Wnek, Joanna Kowalska, Maciej Lukaszewicz, Joanna Zuberek, Edward Darzynkiewicz, Andreas N Kuhn, Ugur Sahin, Jacek Jemielity,

Published in Nucleic Acids Research 44 (2016) 9578-9590

Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential


Structural basis of mRNA-cap recognition by Dcp1–Dcp2

By Jeffrey S. Mugridge, Marcin Ziemniak, Jacek Jemielity, John D. Gross,

Published in Nature Structural & Molecular Biology 23 (2016) 987–994

Structural basis of mRNA-cap recognition by Dcp1–Dcp2


Synthetic Capped mRNAs for Cap-Specific Photo-Cross-Linking Experiments

By Joanna Kowalska, Franck Martin, Jacek Jemielity,

Published in Methods in Molecular Biology 1428 (2016) 31-43

Synthetic m3G-CAP attachment necessitates a minimum trinucleotide constituent to be recognised as a Nuclear Import Signal

By Malgorzata Honcharenko, Burcu Bestas, Martina Jezowska, Blazej A Wojtczak, Pedro Moreno, Joanna Romanowska, Susanna M Bächle, Edward Darzynkiewicz, Jacek Jemielity, C. I. Edvard Smith, Roger Stromberg,

Published in RSC Advances 6 (2016) 51367-51373

Synthetic m3G-CAP attachment necessitates a minimum trinucleotide constituent to be recognised as a Nuclear Import Signal


Fluorescent HTS assay for phosphohydrolases based on nucleoside 5ʹ-fluorophosphates: application in screening for inhibitors of mRNA Decapping Scavenger and PDE-I

By Marek R. Baranowski, Anna Nowicka, Jacek Jemielity, Joanna Kowalska,

Published in Organic & Biomolecular Chemistry 14 (2016) 4595-4604

Fluorescent HTS assay for phosphohydrolases based on nucleoside 5ʹ-fluorophosphates: application in screening for inhibitors of mRNA Decapping Scavenger and PDE-I


Acetylpyrene-labelled 7-methylguanine nucleotides: unusual fluorescence properties and application to Decapping Scavenger activity monitoring

By Renata Kasprzyk, Joanna Kowalska, Zbigniew Wieczorek, Mariusz Szabelski, Ryszard Stolarski, Jacek Jemielity,

Published in Organic & Biomolecular Chemistry 14 (2016) 3863-3868

Acetylpyrene-labelled 7-methylguanine nucleotides: unusual fluorescence properties and application to Decapping Scavenger activity monitoring